期刊论文

Deng, Y.(dy_dengyan@yahoo.com.cn)

英文

JOURNAL OF BIOMEDICAL NANOTECHNOLOGY

1550-7033

2013

9

8

1378-1382

10.1166/jbn.2013.1633

National Key Program for Developing Basic Research of China [2010CB933903]; NSFC [60971045, 21205013, 21205036, 61271056, 61201033]; Hunan Science and Technology Projects [2012SK3105, 2010sk2003]; Natural Science Foundation of Hunan Province [12JJ6060, 12JJ9038]; Scientific Research Fund of Hunan Provincial Education Department [11A030]; China Postdoctoral Science Foundation [2012M520980]

本校为第一且通讯机构

Using two nano-porous pseudo carbon paste electrodes (Nano-PPCPEs) as the working electrodes, a saturated calomel electrode as the reference electrode, and a Pt electrode as the counter electrode to form a four-electrode system, a novel type of glutamate-acetylcholine electrochemical biosensor array was successfully fabricated. It was shown that the biosensor array displayed a high selectivity and sensitivity and the selective and simultaneous determination of glutamate and acetylcholine (ATCh) is feasible. For L-glutamate, a linear range from 5×10^-7 M to 1×10^-5 M with the detection limit of 2.5×10^-7 M was demonstrated, while for ATChI the linear range is from 5×10^-6 M to 2×10^-4 M with the detection limit of 1.5×10^-7 M. This research means a possibility to simultaneously detect more neurotransmitters with a nano-PPCPEs electrochemical biosensor array. Copyright ©2013 American Scientific Publishers All rights reserved.